Discover Hyaluronic Acid (HA) in Wound Healing

Why low molecular weight HA in wound healing?
Why low molecular weight HA in wound healing?
Alberto Passi Department of Medicine and Surgery, Insubria University, Varese, Italy

Hyaluronic acid (HA), also called hyaluronan, is a natural anionic, non-sulphated glycosaminoglycan (GAG) that is distributed widely throughout the body. Structurally, HA is a linear polymer composed of repeating polymeric disaccharides units of D-glucuronic acid and N-acetyl-D-glucosamine, and has the unique capacity to retain a large amount of water. In addition to its high hygroscopic nature, HA has a wide variety of functions and beneficial properties: in addition to antioxidant, anti-inflammatory, viscoelastic, bacteriostatic and anti-oedematous properties, it is highly biocompatible and completely non-immunogenic(1). For these reasons, HA has a wide range of applications in medicine, including wound repair.


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